Zespół badawczy: Prophylaxis of Metabolic Diseases

Miejsce pracy: Institute of Animal Reproduction and Food Research PAS in Olsztyn

Słowa kluczowe: insulin resistance, glucose uptake, myotubes

Tematyka badań:

Insulin resistance, characterized by a decreased biological response to insulin, is a condition that can lead to the development of many diseases, including type 2 diabetes.

In my research, I analyze the relationship between intracellular calcium flow regulation and the insulin sensitivity of skeletal muscles. My work primarily focuses on experimental studies, including skeletal muscle cell cultures, gene silencing, assessment of glucose uptake in myotubes, gene expression analysis using qPCR, and protein expression analysis using the Western Blot technique.

Publikacje:

The Ca2+/Calmodulin-dependent Calcineurin/NFAT Signaling Pathway in the Pathogenesis of Insulin Resistance in Skeletal Muscle. doi: 10.1055/a-2174-7958

The expression of NFAT family genes in subcutaneous adipose tissue before and after weight loss in obese individuals. doi: 10.1016/j.numecd.2024.06.011