Research Team: Programming of Fertility and Development

Place of Work: Institute of Animal Reproduction and Food Research, Polish Academy of Sciences

Keywords: Obesity, Leptin, Ovarian Function, Endocrine Disruption, Fertility

Research Focus:

My fascination with reproductive biology began during my undergraduate research on neonatal microflora acquisition and deepened through my MSc in Reproductive Biology and Clinical Embryology, where I studied human sperm cryopreservation. Currently, as a PhD student, my research explores how obesity-induced endocrine imbalances—particularly altered leptin signalling, affect ovarian function and oocyte quality. My goal is to uncover the molecular mechanisms linking metabolic dysfunction to impaired fertility. Feel free to get in touch at: yashaswishrm@gmail.com.

Publications:

Sharma Y, Galvão AM. (2023). Maternal obesity and ovarian failure: is leptin the culprit? Animal Reproduction. PMCID: PMC9968511

Adamowski M#, Sharma Y#, Molcan T, Wołodko K, Kelsey G, Galvão AM. (2024). Leptin signalling regulates transcriptional differences in granulosa cells from genetically obese mice… Sci Rep 14, 8070. DOI

Sharma Y, Sharma M. (2022). Biophysics of Cryopreservation. Int J Thermodyn. 25(1): 17-27. DOI: 10.5541/ijot.925283

Sharma Y, Sharma M. (2020). Biology of Sperm Cryopreservation. J Infertil Reprod Biol. 8(3):43-48.

Sharma Y, Sharma M. (2021). Effect of Sperm Vitrification on PLC zeta Expression.

Numerous accessible articles on The Biology Notes and Microbe Notes